Faculty Profile

Carlos F. Mendes de Leon, PhD

Carlos F. Mendes de Leon, PhD

  • Professor, Epidemiology
  • 1415 Washington Heights
  • Ann Arbor, Michigan 48109-2029

Dr. Carlos Mendes de Leon is a Professor of Epidemiology at the University of Michigan School of Public Health, where he has been a faculty member since 2011.  Prior to joining the University of Michigan, he was first and Associate Professor and then a Professor of Internal Medicine (Epidemiology) and Preventive Medicine at Rush University Medical Center. From 2008-210, he served as the Director of the Rush Institute for Healthy Aging.  Before joining the Rush Institute for Healthy Aging in 1995, he was an Assistant Professor of Epidemiology at the Yale University School of Public Health.

Dr. Mendes de Leon is a social epidemiologist with a primary interest in the major health problems and health disparities in late life. His work focuses on a broad array of social and psychological determinants that affect the development and progression of disability, cognitive decline and other common, age-related health outcomes. Specific areas of interest include the life-course social conditions that affect physical and cognitive decline in older age, the role of work-related experiences in retirement and post-retirement health trajectories, and health disparities in African American and Arab American populations. He is also involved in several international collaborations in Lebanon and the Netherlands. He is an active member in professional organizations in the fields of gerontology, population health science, and epidemiology, and serves on the editorial board of several scientific journals in these disciplines.

  • PhD, Preventive Medicine and Community Health, University of Texas Medical Branch, TX, 1988
  • M.A. , Clinical Psychology, Radboud University, Nijmegen, The Netherlands, 1983
  • B.A., Psychology, Radboud University, Nijmegen, The Netherlands, 1979

  • Social epidemiology
  • Epidemiology of aging
  • Health disparities
  • Work, retirement and aging
  • Longitudinal data analysis methods

  • Dong L, Freedman VA, Mendes de Leon CF.  The association of comorbid depression and anxiety symptoms with disability onset in older adults.  Psychosomatic Medicine, 2020 (2), 82: 158-164.
  • Kader F, Bazzi L, Khoja L, Hassan F, Mendes de Leon C.  Perceived discrimination and mental well-being in Arab Americans from Southeast Michigan: a cross-sectional study.  Journal of Racial and Ethnic Health Disparities, 2020 (7): 436-445.
  • Weuve, J. D’Souza J, Beck T, Evans DA, Kaufman JD, Rajan KB, Mendes de Leon CF, Adar SD. Long-term noise exposure in relation to dementia, cognition and cognitive decline in older adults.  Alzheimer’s Disease and Dementia, 2020 ePub #33084241.
  • Dong L,  Freedman VA, Sánchez BN, Mendes de Leon CF. Racial and ethnic differences in disability transitions among older adults in the United States. Journal of Gerontology Medical Sciences, 2019; 74(3): 406-411.
  • Pampati S, Alattar Z, Cordoba E, Tariq M, Mendes de Leon C. Mental health outcomes among Arab refugees, immigrants, and U.S. born Arab Americans in Southeast Michigan: a cross-sectional study. BMC Psychiatry. 2018;18(1):379.
  • Ali T, Nilsson CJ, Weuve J, Rajan KB, Mendes de Leon CF.  Effects of social network diversity on mortality, cognition and physical function in the elderly: a longitudinal analysis of the Chicago Health and Aging Project (CHAP). Journal of Epidemiology and Community Health, 2018; 72 (11): 990-996.
  • Pool LR, Burgard SA, Needham BL, Elliott MR, Langa KR, Mendes de Leon CF. Negative wealth shock during late middle age and all-cause mortality in the Health and Retirement Study. JAMA, 2018; 319: 1341-1350.
  • Everson-Rose SA, Mendes de Leon CF, Roetker NS, Lutsey PL, Alonso A. Subclinical cardiovascular disease and changes in self-reported mobility: Multi-Ethnic Study of Atherosclerosis (MESA). Journals of Gerontology Medical Sciences, 2018, 73: 218–224.
  • Weuve J, Barnes LL, Mendes de Leon CF, Rajan KR, Aggarwal NT, Hebert LE, Bennett DA, Wislon RS, Evans DA. Cognitive aging in black and white Americans: Cognition, cognitive decline, and Alzheimer’s disease incidence in a population-based study. Epidemiology, 2018; 29: 151-159.
  • Pool LR, Needham BL, Burgard SA, Elliott MR, Mendes de Leon CF. Negative wealth shock and short-term changes in depression and medication adherence among late middle aged adults: A nested crossover study. Journal of Epidemiology and Community Health, 2017; 71: 758-763.
  • van Zon SKR, Bültmann U, Reijneveld SA, Mendes de Leon CF. Functional health decline before and after retirement: A longitudinal analysis of the Health and Retirement Study. Social Science & Medicine, 2016; 170: 26-34.
  • Weuve J, Kaufman JD, Szpiro AA, Curl C, Puett RC, Beck T, Evans DA, Mendes de Leon CF. Exposure to traffic-related air pollution in relation to progression in disability among older adults. Environmental Health Perspectives, 2016; 124: 1000-1008.
  • Kelley-Moore, J.A., Cagney, K.A., Skarupski, K.A., Everson-Rose, S.A., Mendes de Leon, C.F. Do Local Social Hierarchies Matter for Mental Health? A Study of Neighborhood Social Status and Depressive Symptoms in Older Adults. The journals of gerontology. Series B, Psychological sciences and social sciences, 2016; 71: 369-377.
  • Pool, L.R., Weuve, J., Wilson, R.S., Bultmann, U., Evans, D.A., Mendes de Leon, C.F. Occupational cognitive requirements and late-life cognitive aging. Neurology, 2016: 86: 1386-1392.

  • Gerontological Society of America
  • Society for Epidemiologic Research
  • Interdisciplinary Association for Population Health Science
  • American Psychosomatic Society