Faculty Profile

Siobán D. Harlow, PhD

Siobán D. Harlow, PhD

  • Professor, Epidemiology
  • Professor, Obstetrics and Gynecology
  • Professor, Global Public Health
  • Editor-in-Chief, Women's Midlife Health
  • Director, Center for Midlife Science
  • 6610B SPH I
  • 1415 Washington Heights
  • Ann Arbor, Michigan 48109-2029

As a reproductive epidemiologist, Dr. Harlow's research focuses on understanding patterns of menstrual function and gynecological morbidity across the lifespan, including most recently leadership in studies of the natural history of ovarian aging, development of a staging system for reproductive aging, and studies of the interface between ovarian aging and chronic disease.  Her research encompasses the development and application of statistical methodologies that facilitate quantitative analysis of variation in physiologic processes as well as their application in longitudinal cohort studies.  As Director of the Center for Midlife Science (formerly Center for Integrated Approaches to Complex Diseases), she provides stewardship for both the SWAN and the Michigan Bone Health and Metabolism Study (MBHMS) longitudinal cohort data and fosters research opportunities for junior faculty associated with this Center.  She has chaired 25 dissertations, mentored numerous junior faculty at UM and other research institutions and has over 150 peer-reviewed publications.

  • Dr. Harlow's research interests include reproductive aging, gynecologic health, osteoarthritis, disability and functioning in the midlife, obesity and metabolomics, export-led production, environmental impacts on reproductive function, human rights and gender-based violence and the Michigan Lupus Epidemiology and Surveillance program.

    Dr. Harlow is PI of the Study of Women's Health Across the Nation (SWAN) Michigan site and SWAN Repository and Director of the Center for Integrated Approaches to Complex Diseases.  She was PI of the ReSTAGE Collaboration (Staging Reproductive Aging Across Four Cohorts) (R01AG021543), a multi-study effort to empirically evaluate the 2001 STRAW recommendations for staging reproductive aging and of the effort to update the 2001 STRAW recommendations (R13AG039961 "STRAW+10: Addressing the Unfinished Agenda of Staging Reproductive Aging"). She was Associate Director of the University of Michigan International Institute from 2000-2005 and chaired the U-M President's Advisory Committee on Labor Standards and Human Rights from 2003-2005 and 2008-2012.  She served on the Scientific and Technical Advisory Group, Division of Reproductive Health Research, World Health Organization from 2003-2009.

  • Harlow SD, Karvonen-Gutierrez C, Elliott MR, Bondarenko I, Avis NE, Bromberger JT, Brooks MM, Miller JM, Reed BD. It is not just menopause: symptom clustering in the Study of Women’s Health Across the Nation. Women's Midlife Health. 2017 Jul 27;3(1):2. PMCID: PMC5760187

  • Harlow SD, Dusendang JR, Hood MM, Woods NF. Contraceptive preferences and unmet need for contraception in midlife women: where are the data? Women's Midlife Health. 2017 Sep 11;3(1):6.

  • Hedgeman E, Hasson RE, Karvonen-Gutierrez CA, Herman WH, Harlow SD. Perceived stress across the midlife: longitudinal changes among a diverse sample of women, the Study of Women’s health Across the Nation (SWAN). Women's Midlife Health. 2018 Mar;4(2). doi.org/10.1186/s40695-018-0032-3

  • Novak NL, Lira N, O’Connor KE, Harlow SD, Kardia SL, Stern AM. Disproportionate Sterilization of Latinos Under California’s Eugenic Sterilization Program, 1920–1945. American Journal of Public Health. 2018 May 22:(0):e1-3e1-e3. doi: 10.2105/AJPH.2018.304369. [Epub ahead of print] PMID: 29565671

  • Ylitalo K, Karvonen-Gutierrez CA, Fitzgerald N, Zheng H, Sternfeld B, El Khoudary SR, Harlow SD (2013). Relationship of race/ethnicity, body mass index, and economic strain with longitudinal self-report of physical functioning: Study of women's Health Across the Nation Annals Epidemiology 401-8.
  • Gold EB, Crawford SL, Avis N, Crandall CJ, Matthews KA, Waetjen EL, Lee JS, Thurston R, Vuga M, Harlow SD (2013). Factors related to age at natural menopause: Longitudinal analyses from the Study of Women's Health Across the Nation (SWAN) American Journal of Epidemiology 70-83.
  • Karvonen-Gutierrez C, Harlow S, Jacobson J, Manuso P, Jiang Y (2013). The relationship between longitudinal serum leptin measures and measures of magnetic resonance imaging-assessed knee joint damage in a population of mid-life women Diabetes Medicine.
  • Ylitalo K, Harlow SD, Herman WH (2013). Performance-based physical functioning and peripheral neuropathy in a population-based cohort of mid-life women American Journal of Epidemiology 810-17.
  • Huang X, Harlow SD, Elliott MR (2012). Distinguishing six population subgroups by timing and characteristics of the menopausal transition American Journal of Epidemiology 74-83.
  • Cain KC, Harlow SD, Little RJ, Nan B, Yosef M, Taffe JR, Elliott MR (2011). Bias Due to Left Truncation and Left Censoring in Longitudinal Studies of Developmental and Disease Processes American Journal of Epidemiology 1078-84.